Waterfox is a 64-bit version of Firefox. Waterfox is modified version of the Firefox source code specifically for machines running 64-bit versions of Windows. Software designed for 64-bit Windows editions can take advantage of faster RAM and processing speeds and greater stability in 64-bit systems. Just converting Mozilla's source code for 64-bit Windows isn't enough, Waterfox takes it to another level with unique tweaks which help it exploit the speed of 64-bit systems. Waterfox is made with one thing in mind: speed. Waterfox offers 100% Firefox Add-on Compatibility and 64-bit Plugin Support.
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Note: Waterfox shares the same profile data that Firefox does. Do not run both Firefox and Waterfox at the same time.